Calcium Influx through N-type Channels and Activation of 1 Sk and Trp-like Channels Regulates Tonic Firing of Neurons 2 in the Rat Paraventricular Thalamus
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چکیده
4 Abbreviated title: Tonic firing of PVT neurons 5 6 Adrian YC Wong, Jean-Francois Borduas, Stephen Clarke, Kevin FH Lee, Jean7 Claude Béïque* and Richard Bergeron* 8 9 Ottawa Hospital Research Institute, 451 Smyth Road, Roger Guindon Building, Room 10 3501N, Ottawa, Ontario, Canada, K1H 8M5. 11 Tel: (613) 729-0722, Fax: (613) 729-1266 12 Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth 13 Road, Roger Guindon Building, Room 3501N, Ottawa, Ontario, Canada, K1H 8M5. 14 Tel. 613-729-2068; Fax. 613-729-1266 15 16 *Co-corresponding authors: 17 Jean-Claude BEIQUE 18 Department of Cellular and Molecular Medicine, University of Ottawa; 19 20 Richard BERGERON 21 Ottawa Hospital Research Institute 22 451 Smyth Road, Roger Guindon Building, Room 3501N, Ottawa, Ontario, Canada, K1H 23 8M5; Email: [email protected] and [email protected] 24 25 Number of Pages: 40 26 Number of Figures: 11 27 Number of Words in Abstract: 247 28 Number of Words in Introduction: 501 29 Number of Words in Discussion: 1203 30 31 The authors report NO conflict of interest 32 33 Acknowledgment: Supported by operating grants from Canadian Institutes of Health 34 Research (MOP-79360) awarded to R.B. and J-C.B. (MOP-115061), and an Early 35 Research Award from the Ontario Ministry of Research and Innovation (J-C.B.) 36 37 38 Articles in PresS. J Neurophysiol (September 4, 2013). doi:10.1152/jn.00363.2013
منابع مشابه
Calcium influx through N-type channels and activation of SK and TRP-like channels regulates tonic firing of neurons in rat paraventricular thalamus.
The thalamus is a major relay and integration station in the central nervous system. While there is a large body of information on the firing and network properties of neurons contained within sensory thalamic nuclei, less is known about the neurons located in midline thalamic nuclei, which are thought to modulate arousal and homeostasis. One midline nucleus that has been implicated in mediatin...
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تاریخ انتشار 2013